description
The membranous glomerulonephritis (or GEM) is a kidney disease characterized
by the appearance of a nephrotic syndrome. This is the most frequent cause of
nephrotic syndrome in adults. Its origin is often unknown, but there are 15% of
secondary forms revealing an underlying disease. the membranous
glomerulonephritis. Difficult to treat, it can lead to kidney failure requiring
dialysis or transplantation. The discovery of these genes define biomarkers of
membranous glomerulonephritis, which could greatly improve the monitoring and
prevention of disease.
causes
Nephrotic syndrome is caused by anatomic or functional abnormalities of the
glomerular basement membrane, which is normally impermeable to proteins from a
certain molecular weight (60000 daltons, or 60 kDa): the loss of the selectivity
results passage protein in the urine (which appears when the physiological
capabilities of tubular reabsorption of proteins are exceeded) and thus
proteinuria and hypoproteinemia (despite increased protein synthesis by the
liver).
symptoms
Glomerular disease that manifests clinically as proteinuria, and sometimes by
other devices nephrotic syndrome. Histologically it is characterized by deposits
in the capillary bed between glomerular epithelial cells and the basement
membrane and thickening of the membrane. Also features external projections of
the membrane between the epithelial deposits "transient." There are a number of
arguments that deposits are antibody-antigen complexes.
diagnostic
Vascular thrombosis, protein loss by fighting against platelet
aggregation,
1. hematuria, hypertension, renal failure
2. edema by decreasing the oncotic pressure of plasma,
3. infections, when there is leakage of immunoglobulins and complement,
4. Increased drug toxicity, by increasing the free fraction 5. drugs (which
are normally tightly bound to albumin, and 6. So Inactive: the decrease in
albumin concentration is responsible for an increase in the rate free, and
therefore active drug.)
7. dyslipidemia (increased cholesterol and triglyceride levels by stimulating
the liver)
Venous thrombosis have a special place in the GEM: thrombosis of one (or
both) renal vein is frequent but not specific to the disease. The prevention of
thrombosis is provided by anticoagulation, based on heparin or vitamin K,
indicated when serum albumin falls below 20 g / L.
treatments
In case of edema, the low-salt diet and diuretics are indicated in the usual
way: the combination of a loop diuretic and a product potassium-sparing
(amiloride or spironolactone) is often necessary.
Characteristic treatments
Micro-Chinese Medicine Osmotherapy
immunotherapy
immunotherapy
complications
Complications are possible throughout evolution.
infections:
Infections are:
- Very common.
- Favored by the lower rate of immunoglobulins and proposed treatments.
All types of infections can be observed but emphasize:
- Severity of lung infections.
- The gravity of any even trivial viral infection.
- The frequency of opportunistic infections, to parasites (nematode).
An appropriate antibiotic therapy is required in all cases.
thrombosis:
Thrombosis are also common, favored by hypercoagulability accompanying any
nephrotic syndrome.
Emphasize the renal vein thrombosis complicating especially extra-membranous
glomerulonephritis.
Nitrogen deficiency:
Nitrogen deficiency causes: muscle wasting, osteoporosis, malnutrition.
It is aggravated by corticosteroids.
Abdominal attacks:
The pathogenic hypotheses abdominal pain crises are numerous: mesenteric
edema, pancreatic, deep vein thrombosis.
Do not misunderstand acute appendicitis or peritonitis pneumonia.
Skin complications of chronic edema:
Cutaneous complications of chronic edema are the excoriations and
dermatitis.
A treat with care, as they are a gateway to infection.
Due to the time difference, your message within 48 hours to respond, please
understand. You fill the information will be kept confidential.
2015年1月30日星期五
Chronic renal failure
description
In the United States, about one in 1000 is treated for ESRD and more than 19 million adults living with some form of chronic renal failure. In Canada, about 1.9 to 2.3 million people are suffering from chronic renal failure.
Renal impairment is an impairment of the functioning of the two kidneys and is more properly filter the blood. It is called acute if the dysfunction is transient, chronic when the destruction is irreversible, no cure. In case of severe renal failure, renal function can be overridden by dialysis or kidney transplant.
Chronic kidney disease does not regress, by definition. It is induced by conditions (diabetes, hypertension ...) that destroy gradually and irreversibly different kidney structures. There are five stages of the disease to end-stage filtration capacity which is less than 15% of normal for the entire kidney. This stage requires to consider alternative techniques of renal function: dialysis and transplantation.
causes
The most common causes of chronic kidney disease in North America are diabetes mellitus (diabetes type 1 or 2) and high blood pressure. The most common cause of end-stage renal disease worldwide is IgA nephropathy (inflammatory disease of the kidney).
One of the complications of diabetes and high blood pressure is the appearance of lesions on the small blood vessels of the body, including those found in the kidneys; this results in a chronic renal failure.
1. pyelonephritis (kidney infection) recurrent;
2. polycystic kidney disease (presence of multiple cysts in the kidneys);
3. autoimmune diseases such as systemic lupus erythematosus;
4. hardening of the arteries, which can damage the blood vessels of the kidney;
5. a urinary tract obstruction and reflux attributable to infections and frequent calculations or congenital anatomic abnormality;
6. excessive use of drugs metabolized by the kidneys.
symptoms
Chronic renal failure, regardless of their severity, does not result in significant symptomatology that is to say, the appearance of symptoms or clinical signs and very clear in great numbers. Usually chronic renal failure are diagnosed incidentally. This is the case for example of a blood and urine balance to try to explain the presence of protein in the urine (proteinuria). This is also the case for the diagnosis of hematuria (blood in urine) or high blood pressure.
Sometimes the diagnosis of failure chronic renal failure is in the control of another disease complicating chronic renal failure departure
diagnosis
First there is the strong increase in proteinuria (high concentration of protein in the urine). It also identifies high blood pressure which significantly reduces life expectancy if untreated. Finally, it was found that smoking helps the progression of renal disease and also that smoking cessation slowed the progression of CKD. In the final stage, fluid intake may prove to be dangerous since there may OAP, patients should strongly limit the drinks.
treatments
In France, the course "classic" of a patient with ESRD usually goes through one or more periods of dialysis and one or more kidney transplants. But there are other treatments for chronic renal failure in China, hemodialysis or peritoneal dialysis is possible at The Kidney Hospital of Shijiazhuang. characteristics Therapy The Shijiazhuang Kidney Hospital Chronic renal failure is Micro-Chinese Medicine Osmotherapy and Immunotherapy.
Characteristic treatments
Micro-Chinese Medicine Osmotherapy
immunotherapy
immunotherapy
complications
1.1 anemia;
2. hypertension;
3. an increased risk of bleeding;
4. increased susceptibility to infections;
5. fluid accumulation (edema);
6. dehydration;
7. electrolyte abnormalities (eg hyperkalemia, increased level of potassium in the blood.)
8. abnormal level of minerals in the blood (eg, hypercalcemia or hyperphosphatemia.);
9. an increase in bone fragility;
10. malnutrition;
11. convulsions.
Due to the time difference, your message within 48 hours to respond, please understand. You fill the information will be kept confidential.
In the United States, about one in 1000 is treated for ESRD and more than 19 million adults living with some form of chronic renal failure. In Canada, about 1.9 to 2.3 million people are suffering from chronic renal failure.
Renal impairment is an impairment of the functioning of the two kidneys and is more properly filter the blood. It is called acute if the dysfunction is transient, chronic when the destruction is irreversible, no cure. In case of severe renal failure, renal function can be overridden by dialysis or kidney transplant.
Chronic kidney disease does not regress, by definition. It is induced by conditions (diabetes, hypertension ...) that destroy gradually and irreversibly different kidney structures. There are five stages of the disease to end-stage filtration capacity which is less than 15% of normal for the entire kidney. This stage requires to consider alternative techniques of renal function: dialysis and transplantation.
causes
The most common causes of chronic kidney disease in North America are diabetes mellitus (diabetes type 1 or 2) and high blood pressure. The most common cause of end-stage renal disease worldwide is IgA nephropathy (inflammatory disease of the kidney).
One of the complications of diabetes and high blood pressure is the appearance of lesions on the small blood vessels of the body, including those found in the kidneys; this results in a chronic renal failure.
1. pyelonephritis (kidney infection) recurrent;
2. polycystic kidney disease (presence of multiple cysts in the kidneys);
3. autoimmune diseases such as systemic lupus erythematosus;
4. hardening of the arteries, which can damage the blood vessels of the kidney;
5. a urinary tract obstruction and reflux attributable to infections and frequent calculations or congenital anatomic abnormality;
6. excessive use of drugs metabolized by the kidneys.
symptoms
Chronic renal failure, regardless of their severity, does not result in significant symptomatology that is to say, the appearance of symptoms or clinical signs and very clear in great numbers. Usually chronic renal failure are diagnosed incidentally. This is the case for example of a blood and urine balance to try to explain the presence of protein in the urine (proteinuria). This is also the case for the diagnosis of hematuria (blood in urine) or high blood pressure.
Sometimes the diagnosis of failure chronic renal failure is in the control of another disease complicating chronic renal failure departure
diagnosis
First there is the strong increase in proteinuria (high concentration of protein in the urine). It also identifies high blood pressure which significantly reduces life expectancy if untreated. Finally, it was found that smoking helps the progression of renal disease and also that smoking cessation slowed the progression of CKD. In the final stage, fluid intake may prove to be dangerous since there may OAP, patients should strongly limit the drinks.
treatments
In France, the course "classic" of a patient with ESRD usually goes through one or more periods of dialysis and one or more kidney transplants. But there are other treatments for chronic renal failure in China, hemodialysis or peritoneal dialysis is possible at The Kidney Hospital of Shijiazhuang. characteristics Therapy The Shijiazhuang Kidney Hospital Chronic renal failure is Micro-Chinese Medicine Osmotherapy and Immunotherapy.
Characteristic treatments
Micro-Chinese Medicine Osmotherapy
immunotherapy
immunotherapy
complications
1.1 anemia;
2. hypertension;
3. an increased risk of bleeding;
4. increased susceptibility to infections;
5. fluid accumulation (edema);
6. dehydration;
7. electrolyte abnormalities (eg hyperkalemia, increased level of potassium in the blood.)
8. abnormal level of minerals in the blood (eg, hypercalcemia or hyperphosphatemia.);
9. an increase in bone fragility;
10. malnutrition;
11. convulsions.
Due to the time difference, your message within 48 hours to respond, please understand. You fill the information will be kept confidential.
A case of renal plokystose in the Shijiazhuang Kidney Disease Hospital
A case of renal plokystose in the Shijiazhuang Kidney Disease Hospital
Name: Pierre
Age: 43
Gender: male
Country: France
I am Pierre comes from France, I lès polycystic kidney for 20 years. Lès disease is not serious in the early stage, this is why I do not hold my attention to renal plokystose. Last years lès symptom of polycystic kidney devenent more and more serious, my doctor told me that my kidney cyst is becoming larger is more numerous than before. I am concerned about these conditions. My doctor also told me that he has no treatment lès effective renal polystose in France now I endender by lès that Traditional Chinese medicine is good for renal lès polystose, that's why I came to China.
Traditional Chinese medicine strips is different with other common treatment. I feel so different after traditional Chinese medicine treated. More symptom disappears. My doctor in the Shijiazhuang Kidney Disease Hospital tell me I'm good terms now lès kysts is controlled by traditional Chinese medicine Lés.
If you would lès same problem like me, Chinese traditional medicine The Shijiazhuang Kidney Disease Hospital is good choice for patients with renal lès plokystose.
Due to the time difference, your message within 48 hours to respond, please understand. You fill the information will be kept confidential.
Name: Pierre
Age: 43
Gender: male
Country: France
I am Pierre comes from France, I lès polycystic kidney for 20 years. Lès disease is not serious in the early stage, this is why I do not hold my attention to renal plokystose. Last years lès symptom of polycystic kidney devenent more and more serious, my doctor told me that my kidney cyst is becoming larger is more numerous than before. I am concerned about these conditions. My doctor also told me that he has no treatment lès effective renal polystose in France now I endender by lès that Traditional Chinese medicine is good for renal lès polystose, that's why I came to China.
Traditional Chinese medicine strips is different with other common treatment. I feel so different after traditional Chinese medicine treated. More symptom disappears. My doctor in the Shijiazhuang Kidney Disease Hospital tell me I'm good terms now lès kysts is controlled by traditional Chinese medicine Lés.
If you would lès same problem like me, Chinese traditional medicine The Shijiazhuang Kidney Disease Hospital is good choice for patients with renal lès plokystose.
Due to the time difference, your message within 48 hours to respond, please understand. You fill the information will be kept confidential.
My polycystic kidney is processed by Micro-Chinese Medicine Osmotherapy
I am happy to share with you my experience of polycystic kidney. I was
diagnosed with polycystic kidney in 2002, my doctor told me that polycystic
kidney disease is an inherited and it is difficult to recover completely. Now,
he has not as effective treatment for this disease. But an effective treatment
for polycystic kidney, many patients are recovered by this treatment, which is
called Micro-Chinese Medicine Osmotherapy in China. It works well for polycystic
kidney.
Fortunately, a friend of my grandfather in China, We stayed touch since 2000, I look at the Micro-Chinese Medicine Osmotherapy for polycystic kidney.
He said that Micro-Chinese Medicine Osmotherapy for polycystic kidney is working well. Many of polycystic kidney patients in China is recovered by this treatment the Nephrology Hospital Shijiazhuang.
After checking into the Shijiazhuang Kidney Disease Hospital, the doctors from here to the dialogue to me, and I am treated by Micro-Chinese Medicine Osmotherapy.
After about 20 days, the symptom of polycystic kidney will disappear. I am in good condition now. If you have other questions, consult renal online experts.
Due to the time difference, your message within 48 hours to respond, please understand. You fill the information will be kept confidential.
Fortunately, a friend of my grandfather in China, We stayed touch since 2000, I look at the Micro-Chinese Medicine Osmotherapy for polycystic kidney.
He said that Micro-Chinese Medicine Osmotherapy for polycystic kidney is working well. Many of polycystic kidney patients in China is recovered by this treatment the Nephrology Hospital Shijiazhuang.
After checking into the Shijiazhuang Kidney Disease Hospital, the doctors from here to the dialogue to me, and I am treated by Micro-Chinese Medicine Osmotherapy.
After about 20 days, the symptom of polycystic kidney will disappear. I am in good condition now. If you have other questions, consult renal online experts.
Due to the time difference, your message within 48 hours to respond, please understand. You fill the information will be kept confidential.
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