Symptoms of lupus nephritis will cause some degree of damage to the patient's kidneys, and this damage will be a step by step as the patient's condition worsened, lupus nephritis patients with fever, aching joints butterfly erythema and circumstances of. Different patients with lupus nephritis prognosis grave circumstances are different. In order to prevent the effects of kidney disease brought to timely treatment for lupus nephritis.
Lupus nephritis is the body endogenous (self) antigens occurring immune complex disease, T cell dysfunction accompanied. Patients with lupus nephritis which is available on a variety of anti-autologous tissue composition of antibodies, wherein the anti-DNA antibodies, especially anti-double stranded DNA (native DNA) antibodies more positive effect, patients circulating immune complexes can be separated into natural and single stranded DNA antibodies and antigens; eluted by the above glomerular immunoglobulin antibody binds to native and single-stranded DNA antigen.
Lupus nephritis can occur at any stage of systemic lupus erythematosus, but generally found in 1 after the onset of systemic lupus erythematosus - four years, with a handful of kidney disease as the first performance. In addition to clinical patient with fever, butterfly erythema, joint pain and other symptoms of systemic lupus erythematosus in general, there are clinical manifestations of renal involvement.
According to the pathological changes in lupus nephritis and different clinical manifestations prognosis can be divided into four types:
First, the mild damage type accounted for 35% -50%. Subclinical, only abnormal urine, proteinuria of + or + +, or every 24-hour urine protein less than 1g, microscopic hematuria, normal or mildly impaired renal function, the prognosis is good.
Second, about 20% of nephrotic syndrome. It was typical of nephrotic syndrome, but normal blood cholesterol, with high blood pressure, moderate renal impairment, the prognosis is poor.
Third, chronic nephritis accounted for 35% -50%. Hypertension, proteinuria more, a large number of red blood cells, kidney function decline and even renal failure.
Fourth, rapidly progressive disease progression is rapid, quick deterioration of renal function. Urinary protein, increased red blood cell casts, and often accompanied by fever and other lupus activity performance. Often enter renal failure in the short term.
Shijiazhuang Kidney Disease Hospital
Shijiazhuang Kidney Disease Hospital is located in Shijiazhuang city, capital of Hebei Province, which is adjacent to the capital of China, Beijing. It was founded in 1986 and his name has become more widely known in recent decades.....Read More

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