what causes of proteinuria?

What are the causes of proteinuria it, this is a problem kidney patients and their families a variety of must be considered, proteinuria can be divided into renal and non-renal proteinuria.
(A) renal proteinuria
1. glomerular proteinuria
Seen in acute glomerulonephritis, various types of chronic glomerulonephritis, IgA nephritis, occult nephritis. Secondary seen in lupus nephritis and other autoimmune diseases, diabetic nephropathy, nephritis, kidney arteriosclerosis. Metabolic disorders seen in gout and kidney.
The extent of the lesion filtration membrane damage and proteinuria is divided into two components:
① selective proteinuria: the albumin-based, and a small amount of low molecular weight proteins in urine without large molecular weight proteins (IgG, IgA, IgM, C3, C4), in a semi-quantitative multi +++ +++ - +, typical disease nephrotic syndrome
② non-selective proteinuria: Description glomerular capillary wall rupture of serious damage, the urine has a large molecular weight proteins, such as immunoglobulins, complement; molecular weight of albumin and low molecular weight protein, protein in the urine, immunoglobulin protein / albumin ratio> 0.5, is + - ++++ semi-quantitative and quantitative between 0.5 ~ 3.0g / 24h, common in primary glomerular diseases, such as rapidly progressive glomerulonephritis, chronic nephritis, membranous or mesangial proliferative glomerulonephritis, and secondary glomerular diseases, such as diabetes, nephritis, lupus nephritis. The emergence of non-selective proteinuria prognosis is poor. Strenuous exercise, long march, high temperature, fever, cold environment, stress, congestive heart failure may also occur proteinuria.
Interstitial nephritis, tubular proteinuria 2. The most common variety of causes, renal vein thrombosis, renal artery embolization, heavy metal salts poisoning.
3. proteinuria in renal tissue, also known as secretory proteinuria. Since urine formation, infiltration of protein metabolism caused by renal tubular urine.
(Ii) non-renal proteinuria
1. humoral overflow proteinuria, also known as proteinuria, such as multiple myeloma.
2. Organizational proteinuria urine protein such as cancer, viral infections produce host proteins.

3. The lower urinary protein mixed with urine cause proteinuria seen in urinary tract infections, urinary tract epithelial cell loss and urinary tract mucin secretion.

Shijiazhuang Kidney Disease Hospital

Shijiazhuang Kidney Disease Hospital is located in Shijiazhuang city, capital of Hebei Province, which is adjacent to the capital of China, Beijing. It was founded in 1986 and his name has become more widely known in recent decades.....Read More

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