What is Causes of Polycystic Kidney Disease

Polycystic kidney disease(PKD) causes many cysts to develop in the kidneys. The most common type is an inherited condition called autosomal dominant polycystic kidney disease. With PKD, problems commonly do not develop until the age of 30-50, with some people never developing any problems. The two common problems that develop are high blood pressure and kidney failure. About half of people with PKD develop kidney failure requiring dialysis or a kidney transplant by the age of 60.
An autosomal recessive form of PKD also exists. It appears in infancy or childhood. This form is much less common than autosomal dominant PKS, but it tends to be very serious and gets worse quickly. It can cause serious lung and liver disease, end-stage kidney disease, and it usually causes death in infancy or childhood.

Persons with PKD have many clusters of cysts in the kidneys. What exactly triggers the cysts to form is unknown.