what is Symptoms of esrd?

End-stage renal disease is when the kidneys permanently fail to work.

Symptoms may include:
General ill feeling and fatigue
Itching (pruritus) and dry skin
Headaches
Weight loss without trying
Loss of appetite
Nausea

Other symptoms may include:
Abnormally dark or light skin
Nail changes
Bone pain
Drowsiness and confusion
Problems concentrating or thinking
Numbness in the hands, feet, or other areas
Muscle twitching or cramps
Breath odor
Easy bruising, nosebleeds, or blood in the stool
Excessive thirst
Frequent hiccups
Low level of sexual interest and impotence
Menstrual periods stop (amenorrhea)
Sleep problems, such as insomnia, restless leg syndrome, or obstructive sleep apnea
Swelling of the feet and hands (edema)
Vomiting, especially in the morning

Weight loss
Nausea or vomiting
General malaise
Fatigue
Headache
Hiccups
Itching
Decreased urination
Easy bruising or bleeding
Lethargy
Difficulty breathing
Seizures
Symptoms may remain mild or absent until kidney function drops to less than 20% of normal.

Dialysis is urgent when one or more of the following occurs:
Inflammation of the covering of the heart
Fluid overload or congestive heart failure (CHF) that cannot be managed with medications. In CHF, fluid backs up into the lungs, legs and other parts of the body.
Dangerous elevations of potassium, sodium or acids in the blood. These substances can affect how other organs function.
Confusion, decreased alertness or seizures
Bleeding related to kidney failure that cannot be improved through other means
Severe, unrelenting nausea and vomiting
Dialysis may also be necessary if symptoms affect quality of life or nutritional status. This is especially true if they are accompanied by severely abnormal blood tests.