Berger's disease or IgA nephropathy

Shijiazhuang Kidney Disease Hospital China

description
Berger's disease is the most common glomerulonephritis (nephritis characterized by selective involvement of glomeruli) chronicles. It represents 25 to 30% of primary glomerular diseases (diseases exclusively due to a violation of glomeruli) and especially in young subjects, with a marked male predominance. This condition occurs throughout the world, but seems more common in Southeast Asia and Europe (especially France and the Iberian peninsula) and in North America.
causes
It seems that there is a genetic predisposition, but the trigger is often infectious or bacterial or viral. The infectious episode is not specific. It may be bronchitis, sinusitis, gastro-enteritis.
symptoms
The main symptom, macroscopic hematuria with or without proteinuria appears during the febrile (intra-infectious). This transitional gross hematuria (2-3 days) with brown urine without clots is present in 30-40% of cases; some patients macroscopic hematuria repeated at each infectious episode, highly suggestive of the diagnosis. The fortuitous discovery of microscopic hematuria and / or proteinuria in the strip during a systematic review is currently less common, as preventive medicine (school, military, academic, labor) is less active than in the past.
diagnosis
Diagnosis is based on renal biopsy remains indispensable. Immunofluorescence lesions are characterized by granular deposits, diffuse and generalized IgA in the mesangium (intercapillary) all glomeruli are affected and all of the glomerulus is reached. Include other deposits, including C3 and other immunoglobulins (IgG or IgM), but the IgA deposits are predominant.
treatments
IgA nephropathy is responsible for 10% of annual new cases of end-stage renal failure requiring dialysis. So it is a relatively common condition that should be diagnosed as early as possible, especially as, contrary to some misconceptions, it can and should be treated. Corticosteroid treatment and control of hypertension and proteinuria with an ACE inhibitor or antagonist of angiotensin 2 improves prognosis.
Characteristic treatments
Micro-Chinese Medicine Osmotherapy
immunotherapy
immunotherapy
complications
1. Hypertension
2. Acute renal failure
3. Chronic renal failure.
4. The nephrotic syndrome

Shijiazhuang Kidney Disease Hospital

Shijiazhuang Kidney Disease Hospital is located in Shijiazhuang city, capital of Hebei Province, which is adjacent to the capital of China, Beijing. It was founded in 1986 and his name has become more widely known in recent decades.....Read More